Issue 1: Vol: 3 (June 2008)
Focus: Patents (Inventions)
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Magnetic bone implants

If the bionic man ever becomes reality, his skeleton may be magnetic.

Artificial bone implants can help fix damaged skeletons, but they can also prevent the healthy growth of natural bone around the implant, weakening the bond between them.

Various ways of encouraging growth and preventing infection have been tried – among them impregnating bone implants with growth hormones and using anti-inflammatory drugs and antibiotics. But these methods provide only a single dose of treatment and if the problem recurs there is little that can be done to treat it without surgery.

One possibility is to attach the drug to magnetic particles and steer them through the body to the relevant site using an external magnetic field. But using that field to hold the drug-bearing particles in place for hours or days is impractical.

Making bone implants magnetic, so that the particles simply stick to them, could get around that, says Zachary Forbes, a surgeon at Drexel University College of Medicine in Philadelphia, US.

He adds magnetic powder to the biopolymer used in bone implants so that they can be made magnetic for an extended time, using the same strong magnetic field used to steer drug particles.

Read the full magnetic bone implant patent application.


Cow udder plugger

Mastitis, a bacterial infection of the mammary glands, can be a significant problem for cow farmers. Up to now they have treated cows by dipping their infected teats into an antibacterial solution – but that can contaminate milk, so any that is produced by the affected cows must be discarded for a time.

Norman Williamson, an expert on bovine health at Massey University in Auckland, New Zealand, has an answer, which he calls an "udder plugger".

Bacteria are usually prevented from entering teats by a plug made of the protein keratin, he explains. Milking, and modern milking machines in particular, can suck out this plug and allow the bacteria in.

Williamson's solution is simply to plug the teat again using keratin mixed with fat that can then be injected or rolled into a plug-shape and pushed in by hand. He has tested the idea on a number of cows and found that it does not irritate the teat. "The way now appears clear to further test the product in dairy cows," he says.

Read the full cow udder plugger patent application.


Supergrass for superlawns

One of the most common grasses chosen for gardens and for planting along roadsides in the southeast US is bahiagrass (Paspalum notatutri). It is popular because it flourishes in poor-quality soil, is resistant to many insects and tolerates conditions of drought and heat.

It may sound ideal, but Fred Altpeter and colleagues at the University of Florida in Gainesville, US, think they can improve it.

Bahiagrass grows 60cm seed heads during the summer, so it must be mowed regularly. It also has a low-density growth pattern that allows weeds to invade.

Altpeter says that adding just one gene to bahiagrass from every geneticist's favourite plant, Arabidopsis thaliana, fixes both those problems.

That gene, Arabidopsis ATHB 16 protein, suppresses the formation of seed heads and encourages bahiagrass to spread out more underground. The modified plant has performed well in tests but whether people will want GM grass along their roadsides and on the lawns is another matter.

Read the full GM supergrass for superlawns patent


Magnetic banknotes

There is a continual battle between counterfeiters and banknote manufacturers. But Stuart Eaton and colleagues at UK military research company Qinetiq think they have designed the only technology that makes it possible for anyone to spot a fake by touch alone.

Most anti-counterfeiting techniques use visual cues such as watermarks or holograms, or machine-readable features like markings that only become visible under ultraviolet light.

Qinetiq's idea is to use spots of magnetic inks on a document such as a banknote, with alternating polarity.

To check a note's authenticity, you simply fold the note and rub it to feel the alternate attraction and repulsion as the inks move past each other.

The sensation would make a smooth piece of paper feel rippled, say the group, who think the technology could work on anything from passports to legal letters. Whether the idea would make notes difficult to stack or peel apart, we can only guess.

A touch-based system would have advantages in places where lighting is poor such as pubs and clubs, as well as being a useful aid to the visually impaired.

The public could be educated to learn how to recognise the particular pattern, says the patent, but no mention is made of how easy or difficult it would be for fraudsters to copy the design.

Read the full magnetic banknotes patent application.



Explosion-absorbing foam

Concussion and longer-lasting brain damage caused by the compression waves from explosions are a growing problem for the military. Carbon foam able to absorb a blast could help tackle that.

A team funded by the US Army Space and Missile Defense Command in Huntsville, Alabama, has developed panels of carbon foam with pores varying in size from 50 micrometres to 2 millimetres.

Carbon foam is made by heat-treating particular materials made from carbon fibres. In tests, panels of the foam absorbed up to 83% of the energy of a blast wave from the detonation of 2 kilograms of C4 explosives at a distance of only 20 centimetres.

This is possible because the foam's pores collapse when hit by a compression wave, absorbing its energy.

The team says the material could be used to protect rooms and vehicles and, if used to enclose explosives, could prevent their accidental detonation when caught in a blast.

Read the full explosion-absorbing foam patent application.



Antibody adapters

Antibodies bind onto foreign substances – antigens – inside the body. Much like a key must fit its lock they need a 3D structure to be able to latch onto their specific antigen.

However, many antigens such as HIV – the virus that causes AIDS – seem impervious to this kind of attack and no known antibody is able to bind to them.

Peter Kwong at the National Institutes of Health Dale and Betty Bumpers Vaccine Research Center in Washington, DC, US, thinks it may be possible to trick the immune system into latching onto these untouchable antigens.

His idea is to design a kind of protein "adapter" that can bind to the antigen on one end and an existing antibody at the other, allowing the antigen to be neutralised.

Kwong and his colleagues have come up with a method of designing these structures on computer and say the approach could provide a new way to fight diseases, such as HIV, that have resisted other approaches.

This will not be an easy process, though – the shapes of antigens and antibodies are hugely complex. Even calculating what they look like requires cutting-edge computer-modelling tools. Predicting what kind of protein could modify that shape is even harder.


Read the full antibody adapter patent application.

Source: www.newscientist.com

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